
Optimal Designs for Discriminating Between some Extensions of the Michaelis-Menten Model
Jesus Lopez Fidalgo, University of Salamanca
Chiara Tommasi, University of Milano
Camelia Trandafir, University of Salamanca
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ABSTRACT:
In this paper some results on the problem of computing optimal
designs for discriminating between rival models are provided.
Using T-optimality for two rival models a compound criterion is
developed to discriminate between more than two models. Surprising
results arise when T-optimal designs are compared with classical
c-optimal designs for nonlinear models. In particular, some
practical deviations of the Michaelis-Menten model are considered
in order to measure and compare efficiencies of different designs.
SUBJECT AREA:
C99
SUGGESTED CITATION:
Jesus Lopez Fidalgo, Chiara Tommasi, and Camelia Trandafir,
"Optimal Designs for Discriminating Between some Extensions of the Michaelis-Menten Model"
(April 2005).
UNIMI - Research Papers in Economics, Business, and Statistics.
Statistics and Mathematics.
Working Paper 2.
http://services.bepress.com/unimi/statistics/art2
Paper presented by Pieralda Ferrari.
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